Drug Standards
Medchemexpress LLC Tenofovir Disoproxil | 201341-05-1 | 99.5% | 519.44 | 100 MG
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor. It is used to treat HIV and chronic Hepatitis B, and is intended for research use only.
- Nucleotide reverse transcriptase inhibitor
- Used to treat HIV
- Used to treat chronic Hepatitis B
- Solid appearance
- White to off-white color
- Purity 99.5%
- For research use only
Medchemexpress LLC (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine compound with (3S,4S)-1-benzyl-N,4-dimethyl piperidin-3-amine (1:1) | 95.4% | 436.69 | 25 MG
Tofacitinib impurity 2 is an impurity of Tofacitinib (HY-40354) and is intended for research use only. This product is not for human use.
- Molecular weight of 436.69
- Formula C28H44N4
- Appearance: liquid
- Purity of 95.42% by LCMS
- Storage at 4°C, protected from light
- In solvent storage at -80°C for 6 months or -20°C for 1 month, protected from light
Sigma Aldrich Fine Chemicals Biosciences Tinidazole Related Compound A United States Pharmacopeia (USP) Reference Standard | 696-23-1 | MFCD00151322 | 100MG
Tinidazole Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 127.1 | 696-23-1 | MFCD00151322 | 100MG
Sigma Aldrich Fine Chemicals Biosciences Lactulose European Pharmacopoeia (EP) Reference Standard | 4618-18-2 | MFCD00151469 |
Lactulose European Pharmacopoeia (EP) Reference Standard | Mol Wt: 342.3 | 4618-18-2 | MFCD00151469 |
Sigma Aldrich Fine Chemicals Biosciences Dermatan sulfate United States Pharmacopeia (USP) Reference Standard | 54328-33-5 | MFCD00151683 | 25MG
Dermatan sulfate United States Pharmacopeia (USP) Reference Standard | 54328-33-5 | MFCD00151683 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Rifampicin European Pharmacopoeia (EP) Reference Standard | 13292-46-1 | MFCD00151389 |
Rifampicin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 822.94 | 13292-46-1 | MFCD00151389 |
Medchemexpress LLC Racemic voriconazole | 188416-29-7 | MFCD09263753 | 99.1% | 349.31 g/mol | C16H14F3N5O | 25 MG
(±)-Voriconazole (racemic voriconazole) is the racemic form of the second-generation triazole antifungal, supplied for research use. It acts as a broad-spectrum inhibitor of fungal ergosterol biosynthesis and is provided as a high-purity research chemical.
- Racemic configuration (mixture of enantiomers).
- Second-generation, broad-spectrum antifungal activity.
- Inhibits fungal ergosterol biosynthesis.
- High purity (99.06%).
- Molecular weight 349.31 g/mol; formula C16H14F3N5O.
- Provided as a research-grade chemical for laboratory use.
Medchemexpress LLC Alverine citrate | 5560-59-8 | 99.5% | 10 MM 1 ML
Alverine citrate is a 5-HT1A receptor antagonist with an IC50 of 101 nM, primarily used for research and analytical applications. It acts directly on gut muscles, causing relaxation, and is used in studies of functional gastrointestinal disorders. This compound shows high affinity for 5-HT1A receptors and weak affinity for 5-HT3 and 5-HT4 subtypes.
- 5-HT1A receptor antagonist
- IC50 of 101 nM
- Used for research and analytical applications
- Relaxes gut muscles
- High affinity for 5-HT1A receptors
- Molecular formula: C26H35NO7
- Molecular weight: 473.56
- Appearance: White to off-white solid
Sigma Aldrich Fine Chemicals Biosciences Metronidazole impurity A European Pharmacopoeia (EP) Reference Standard | 696-23-1 | MFCD00151322 |
Metronidazole impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 127.1 | 696-23-1 | MFCD00151322 |
Medchemexpress LLC Osimertinib | 1421373-65-0 | MFCD27988062 | 99.7% | 499.61 g/mol | C28H33N7O2 | 10 MG
Osimertinib (Standard) is an analytical reference standard intended for research and analytical applications. The standard is supplied at high purity and is commonly used for qualitative, quantitative, and method development work in HPLC, GC, and MS.
- High purity suitable for analytical use (99.69%).
- Intended for qualitative, quantitative, and methodological research.
- Suitable for HPLC, GC, and MS method development and validation.
- Available in multiple package sizes, including small reference quantities such as 10 mg.
- Supplied with supporting documentation, including COA and SDS for traceability.
Apexbio Technology LLC Methylprednisolone Sodium Succinate 2375-03-3 10mg
Methylprednisolone sodium succinate is a synthetic glucocorticoid with anti-inflammatory and immunomodulatory activity routinely utilized as an experimental tool in inflammation immune response and neural injury studies Mechanistically it binds cytoplasmic glucocorticoid receptors modulating transcriptional activity to suppress cytokine release reduce circulating lymphocyte counts and promote apoptosis and differentiation in responsive cells In vitro assays demonstrate inhibition of neutrophil-mediated chemotaxis and suppression of reactive oxygen species production at high concentrations ( 1 mg/ml) whereas lower concentrations (0 04 0 22 mM) exhibit minimal effects The IC50 values reported for suppression of neutrophil chemiluminescence and oxidant generation are approximately in the millimolar range (around 2 7 mM) Clinically it has been studied for central nervous system injuries including spinal cord trauma
Apexbio Technology LLC Pantoprazole 102625-70-7 10mM (in 1mL DMSO)
Pantoprazole is an inhibitor of H /K -ATPase frequently utilized in biomedical research to explore mechanisms related to gastric acid secretion and intracellular acidification Upon acid-activated conversion to its sulfenamide derivative pantoprazole irreversibly binds to cysteine residues (Cys813 and Cys822) in gastric parietal cell proton pumps thus suppressing proton transport and subsequent acid secretion Pantoprazole also impairs lysosomal acidification with an IC50 value of approximately 194 M Its reported antimicrobial activity against Helicobacter pylori expands its experimental application making pantoprazole suitable in studies involving gastric physiology proton pump enzymology lysosomal function and bacterial pathogenesis
Medchemexpress LLC S-diclofenac | 912758-00-0 | 99.2% | 504.47 g/mol | C23H15Cl2NO2S3 | 10 MG
S-diclofenac is a hybrid molecule that combines an H2S donor with the nonsteroidal anti-inflammatory scaffold of diclofenac. It shows multifaceted biological activity including activation of the p53 signaling pathway, inhibition of JNK, antioxidant effects, and anti-inflammatory activity, and has been used in both in vitro and in vivo research models to study inflammation, oxidative stress, and cardiac injury.
- Activates the p53 signaling pathway and upregulates downstream effectors.
- Inhibits JNK activation, modulating stress-related signaling.
- Exhibits antioxidant and anti-inflammatory properties.
- Demonstrates efficacy in animal models of edema and myocardial injury.
- Provided at high listed purity to support research reproducibility.
- Available as small solid packages and as a solution in DMSO for convenience.
- Solid appearance described as reddish brown to red.
Apexbio Technology LLC Flavopiridol hydrochloride 131740-09-5 1g
Flavopiridol hydrochloride is a selective inhibitor of cyclin-dependent kinases (CDKs) specifically targeting CDK1 CDK2 CDK4 and CDK6 with reported IC50 values approximately 41 nM and CDK7 with an IC50 of about 300 nM Additionally it has been observed to inhibit EGFR and protein kinase A at micromolar concentrations By inhibiting CDK activity flavopiridol hydrochloride disrupts cell cycle progression inducing G1 phase arrest as demonstrated in breast cancer cell lines Furthermore its capacity to inhibit phosphorylation of Rb protein and suppress anti-apoptotic proteins such as Mcl-1 and XIAP facilitates apoptosis in lymphoma cell models Flavopiridol hydrochloride is utilized in preclinical studies of cell cycle regulation apoptosis signaling and cancer research including experiments using xenograft tumor models in mice